TreeFam is a database composed of phylogenetic trees inferred from animal genomes. It provides orthology/parology predictions as well the evolutionary history of genes.
(see the BRCA2 gene family page as an example).
Feature: TreeFam family visualisation available:
[...] Feature: Tree Insertion available:
[...]
Suggestion: Downloading the full gene tree view:
[...] Suggestion: Domain diagrams as hyperlinks to Pfam:
[...]
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[...] TreeFam: What is in the next release: [...]
We are on the move: [...]
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Learn about how TreeFam builds families, alignments, and trees and how families defined in TreeFam.
TreeFam families
There are many ways you can link to TreeFam data. Learn how you can link to e.g. our gene families.
Gene tree widget
You can add our gene tree widget to your website: e.g. simply point an iframe to our trees using a TreeFam family ID or a sequence identifier.
Protein domains: 
RNA families: 
Repetitive DNA: 
Peptidases: 
Spurious ORFs: 
Data download
Download all our data: e.g. alignments, hmms, trees, pairwise orthologs, external references and more.
API
Programmatically fetch data through our API and see a list of example scripts in our 永久免费加速. Use treefamscan to score your sequences against TreeFam hmms.
Citing
If you find TreeFam useful, please consider
citing the references
that describe this work:
TreeFam: 2008 Update
Nucleic Acids Research (2008)
doi: 10.1093/nar/gkm1005